The Los Angeles Rams seek to win their second consecutive game as they head on the road to face the Arizona Cardinals. The Rams (4-6) edged Seattle, 17-16 on Sunday, while Arizona (2-9) lost a tight game in Houston, 21-16. Los Angeles won the teams' earlier matchup this season, 26-9 in Week 6.

Kickoff from State Farm Stadium in Glendale is set for 4:05 p.m. ET. Los Angeles is a 3-point favorite in the Cardinals vs. Rams odds via SportsLine consensus, while the over/under is 45. Before making any Arizona vs. Los Angeles picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2023 NFL season on an incredible 175-126 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 29-18 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, it has simulated Rams vs. Cardinals 10,000 times and the results are in. We can tell you that the model is leaning Under the total, and it also says one side of the spread hits more than 50% of the time! You ABSOLUTELY need to see it before locking in your own picks. 

Who wins Rams vs. Cardinals, and which side of the spread hits more than 50% of the time? Join SportsLine right now to find out which side of the Cardinals-Rams spread is a MUST-BACK, all from the model on a 175-126 roll on NFL picks!