The No. 2 Alabama Crimson Tide will play their first road game of the season when they face the No. 13 Purdue Boilermakers on Friday night. Alabama has opened the season with three wins over unranked opponents, so this is an opportunity to boost its resume early in the campaign. Purdue has won 38 consecutive regular-season non-conference games, which is the fifth-longest streak in NCAA history.  

Tipoff is set for 7 p.m. ET on Friday at Mackey Arena. Alabama is favored by 2.5 points in the latest Purdue vs. Alabama odds, while the over/under is 164.5 points, per SportsLine consensus. Before entering any Alabama vs. Purdue picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 2 of the 2024-25 season on a 155-110 betting roll (+2102) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen HUGE returns!

The model has simulated Purdue vs. Alabama 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in nearly 80% of simulations.

So who wins Alabama vs. Purdue, and which side of the spread hits nearly 80% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!