The 2021 ACC Championship will be decided with a matchup between the Pittsburgh Panthers and the Wake Forest Demon Deacons at 8 p.m. ET on Saturday. Pittsburgh is favored by 3.5 points at Caesars Sportsbook, while the Over-Under is set at 72 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Pittsburgh vs. Wake Forest picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,700 for $100 players on its top-rated college football picks against the spread. It also enters Championship Week 2021 on a 42-28 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The model knows Pittsburgh is electric on offense. The Panthers are No. 4 in the country in both total offense (514.3 yards per game) and scoring offense (42.8 points per game), with an elite-level passing attack. Kenny Pickett keys a group that is generating more than 350 yards per game through the air, and Pittsburgh leads the ACC in passing touchdowns, yards per attempt and completion rate. Pittsburgh is also No. 2 in the ACC on third down, converting 47.2 percent of the time.

The model also knows Wake Forest is more than capable of explosiveness on offense. The Demon Deacons lead the ACC in scoring, averaging 42.9 points per game, and Wake Forest is in the top ten in total offense with more than 480 yards per game. The Demon Deacons are also leading the conference in third down efficiency at 50.8 percent in 2021. Wake Forest has allowed only 26 sacks all season, and the Demon Deacons are tied for the ACC lead with 29 rushing touchdowns.

Now, it has set its sights on Pittsburgh vs. Wake Forest. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Pittsburgh vs. Wake Forest? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to find out which side of the Pittsburgh vs. Wake Forest spread you should be all over Saturday, all from the model on a roll on college football picks!