The Portland Trail Blazers will face off against the Detroit Pistons at 7 p.m. ET on Monday at Little Caesars Arena. Detroit is 17-18 overall and 8-8 at home, while Portland is 12-22 overall and 4-14 on the road. The Pistons are favored by 6.5 points in the latest Pistons vs. Trail Blazers odds, and the over/under is 224.5 points.

Before entering any Pistons vs. Trail Blazers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 11 of the 2024-25 NBA season on a sizzling 128-95 roll on all top-rated NBA picks dating back to last season, returning nearly $3,000. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Pistons vs. Trail Blazers 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that hits in well over 50% of simulations. 

So who wins Pistons vs. Trail Blazers? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.