loading...
League Logo
NBA
League Logo
NBA
League Logo
MLB
League Logo
NHL
All
  • Loading...
loading...

Pistons vs. Knicks odds, line: Proven model reveals picks for NBA first-round matchup on April 21, 2025

The SportsLine Projection Model, up well over $10,000 on NBA picks over the past six seasons, has locked in its bets for the Detroit Pistons vs. New York Knicks Game 2 matchup on Monday

ByPublished: Apr 21, 2025 9:08PM UTC . 2 min read

The third-seeded New York Knicks look to take a commanding 2-0 series lead when they battle the sixth-seeded Detroit Pistons in Game 2 of their Eastern Conference first-round matchup on Monday. The Pistons (44-38), who placed fourth in the Central Division, are 22-20 on the road so far this season. The Knicks (51-31), who were second in the Atlantic Division, are 28-14 at home in 2024-25. Isaiah Stewart (knee) is questionable for Detroit, while New York has no injuries to report.

Tip-off from Madison Square Garden in New York is set for 7:30 p.m. ET. The teams have split their 16 all-time postseason meetings. The Knicks are 7-point favorites in the latest Pistons vs. Knicks odds, while the over/under for total points scored is 221. New York is at -271 on the money line (risk $271 to win $100), while Detroit is at +219 (risk $100 to win $219).

Before making any Pistons vs. Knicks picks, check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the first full week of the 2025 NBA playoffs on a sizzling 156-116 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It is also 22-11 (67%) on top-rated NBA against-the-spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Pistons vs. Knicks 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits well over 50% of the time!

GET VEGAS EXPERT PICKS FOR NFL, MLB, NBA, CBB, GOLF, NHL, HORSE RACING AND MORE - PLUS ADVANCED COMPUTER SIMULATIONS, WINNING TOOLS, AND MORE!

JOIN NOW
Avatar
Daniel Kohn

Share This Story

SportsLine Logo
YOU'VE UNLOCKED OUR BEST DEAL!
GET YOUR FIRST QUARTER OF SPORTSLINE FOR 50% OFF WITH PROMO CODE 'CLUB'!
© 2025 CBS INTERACTIVE INC. ALL RIGHTS RESERVED. SportsLine and SportLine PRO are registered trademarks of SportsLine.com, Inc.FANS ONLY
In partnership with...247 Sports

FOLLOW US:

The content on this site is for entertainment purposes only and SportsLine makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. There is no gambling offered on this site. This site contains commercial content and SportsLine may be compensated for the links provided on this site.