The Detroit Pistons will try to build on their first victory of the season when they host the New York Knicks on Friday night. Detroit lost its first four games of the campaign, but it bounced back with a 105-95 win at Philadelphia on Wednesday. New York is going on the road for the second game in a row after beating Miami by nine points earlier this week. 

Tipoff is set for 7 p.m. ET on Friday at Little Caesars Arena. The Knicks are favored by 6.5 points in the latest Pistons vs. Knicks odds, while the over/under is 216.5 points, per SportsLine consensus. Before entering any Knicks vs. Pistons picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 2 of the 2024-25 NBA season on a sizzling 98-63 roll on all top-rated NBA picks dating back to last season, returning more than $2,900. Anyone following has seen HUGE returns!

The model has simulated Pistons vs. Knicks 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Knicks? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.