The Philadelphia Phillies and Toronto Blue Jays meet in the second of a two-game series on Wednesday in a key interleague matchup. Philadelphia rallied from a five-run deficit to post a 10-9 win on Tuesday night. The teams split two games earlier in the year in Philadelphia.

First pitch is scheduled for 3:07 p.m. ET from Rogers Centre in Toronto. The Phillies are the -125 money-line favorites (risk $125 to win $100) in the latest Phillies vs. Blue Jays odds, while the Blue Jays are +106 underdogs. The over/under for total runs scored is 8 in the latest MLB odds via SportsLine consensus. 

Before you make any Phillies vs. Blue Jays picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. Entering Week 24 of the MLB season, it's on a 30-15 roll on top-rated run-line picks (+863) that dates back to last season. Anybody following has seen STRONG returns!

The model knows first baseman Bryce Harper is among Philadelphia's leaders on offense. The 12-year veteran has played in 122 games this season and is batting .282 with 34 doubles, 26 homers, 76 RBI and 73 runs scored. He has five multi-hit games over the past eight, including a 3-for-4 performance with two doubles in a 7-2 loss to Atlanta on Friday. He was 2-for-6 on Tuesday. In 22 career games against the Blue Jays, Harper is hitting .293 with five doubles, five homers and 13 RBI.

The model also knows helping power the Toronto offense is first baseman Vladimir Guerrero Jr., who has been on a tear of late. Over the last nine games, he has seven multi-hit performances, including a 4-for-5 performance on Tuesday with a double, one home run and two RBI. He was 3-for-5 at Minnesota on Saturday. In 137 games this season, he is batting .328 with 39 doubles, one triple, 28 homers, 91 RBI and 84 runs scored. In 19 career games against Philadelphia, he is hitting .277 with two doubles, five homers and 11 RBI.

The model has simulated Phillies vs. Blue Jays 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

Who wins Phillies vs. Blue Jays, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 30-15 roll on top-rated MLB run-line picks!