The Carolina Panthers (0-4) hit the road looking for their first win of the season when they take on the Detroit Lions (3-1) in a NFL Week 5 matchup on Sunday. The Panthers fell 21-13 to the Minnesota Vikings at home in Week 4. The Lions, on the other hand, are looking to win their third straight game after defeating the Green Bay Packers 34-20 on Thursday Night Football.

Kickoff at Ford Field is scheduled for 1 p.m. ET. Detroit is a 9.5-point favorite and the over/under for total points scored is 44 in the latest Lions vs. Panthers odds. Before making any Panthers vs. Lions picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2023 NFL season on an incredible 168-118 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 22-10 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has set its sights on Panthers vs. Lions. We can tell you the model is leaning Under on the point total, and it also says one side of the spread hits more than 50% of the time! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Panthers vs. Lions, and which side of the spread hits more than 50% of the time? ... Join SportsLine right now to find out which side of the Lions vs. Panthers spread is a MUST-BACK, all from the model on a 168-118 roll on NFL picks!