The Cincinnati Bengals will face off against the Carolina Panthers ina cross-conference showdown at 1 p.m. ET on Sunday at Bank of America Stadium. Carolina is 1-2 overall and 0-1 at home, while Cincinnati is 0-3 overall and 0-1 on the road. The Bengals are looking to bounce back from a 38-33 loss to the Washington Commanders and will be looking to avoid an 0-4 start to the season. The Panthers upset the Las Vegas Raiders in Week 3, winning 36-22 with Andy Dalton starting at quarterback. 

The Bengals are favored by 4.5 points in the latest Panthers vs. Bengals odds, and the over/under is 47 points. Before entering any Panthers vs. Bengals picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2024 NFL season on an incredible 188-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 42-22 roll on top-rated NFL picks since Week 7 of 2022. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

The model has simulated Panthers vs. Bengals 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations!

So who wins Panthers vs. Bengals, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks!