The surprising Oklahoma Sooners (6-1) take on the slow-starting Villanova Wildcats (2-5) on Saturday in the Big 12-Big East Battle at Wells Fargo Center in Philadelphia. This is the first meeting between the teams since the Wildcats annihilated the Sooners 95-51 in the 2016 Final Four on their way to winning the national championship.   

Tip-off is scheduled for 12:30 p.m. ET. The Wildcats are favored by 3 points in the latest Oklahoma vs. Villanova men's college basketball odds at Caesars Sportsbook, and the over/under is set at 125.5 (see up-to-date odds for every game this week on our college basketball odds page). Saturday's game can be seen live on CBS and streamed live on Paramount+, which you can get 50% off for one year when you use promo code ALLYEAR from now until 12/31.

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Before making any Villanova vs. Oklahoma picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past six-plus years, the proprietary computer model has generated more than $1,500 for $100 players on its top-rated college basketball picks against the spread. Anybody who has followed it has seen profitable returns.

The model knows Villanova has the pedigree and still has plenty of talent. Eric Dixon (17.6 points, 6.4 rebounds), Caleb Daniels (17.4, 5.4) and Brandon Slater (11.7, 6.0) all are capable scorers who can hit the glass. The defense has been shaky, but the Wildcats average almost five more points per game than the Sooners. OU has scored more than 70 points twice this season while Nova has done so five times.    

The model also knows Oklahoma has been building a lot of confidence and just knocked off an unbeaten team. They beats Ole Miss 59-55, and they allow 14 points fewer per contest. The Sooners are tied for 15th in the nation (56.9 points per game), while Nova is tied for 232nd (71 ppg). Guard Grant Sherfield is hitting 45.3 percent of his attempts from 3-point range, and he is averaging 15.6 points and five assists.      

Now, the model has set its sights on Oklahoma vs. Villanova, and it is leaning Over on the total and it also says one side of the spread hits in well over 60% of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

So who wins Villanova vs. Oklahoma in Saturday's Big East-Big 12 Battle matchup? And which side of the spread hits in well over 60% of simulations? Join SportsLine now to find out, all from the model that has crushed its top-rated college basketball picks against the spread!