The No. 4 Ohio State Buckeyes will try to bounce back from their first loss of the season when they host the Nebraska Cornhuskers on Saturday afternoon. Ohio State had its five-game winning streak snapped in a 32-31 loss at then-No. 3 Oregon two weeks ago, but it had an extra week to prepare for this game. Nebraska is hoping for a much better performance following a 56-7 loss at then-No. 16 Indiana last week.  

Kickoff is set for noon ET on Saturday at Ohio Stadium. Ohio State is favored by 25.5 points in the latest Ohio State vs. Nebraska odds, while the over/under is 48.5 points, per SportsLine consensus. Before entering any Nebraska vs. Ohio State picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 14-7 on all top-rated picks over the past four weeks of this season. Anyone following has seen STRONG returns!

The model has simulated Ohio State vs. Nebraska 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60% of simulations!

So who wins Ohio State vs. Nebraska? And which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!