The Ohio State Buckeyes will host the No. 18 Michigan State Spartans in Big Ten action on Friday. Ohio State is 9-4 overall, including 1-1 in the Big Ten. Michigan State is 11-2 overall, including 2-0 in the Big Ten. The Buckeyes are coming off a 103-83 non-conference victory over Indiana State on Sunday. The Spartans are coming off an 80-62 non-conference win over Western Michigan on Monday. Ohio State defeated Michigan State, 60-57, on the road in their only matchup last season.

Tipoff is set for 8 p.m. ET on Friday from Value City Arena at the Jerome Schottenstein Center in Columbus, Ohio. Ohio State is favored by 2.5 points in the latest Michigan State vs. Ohio State odds, while the over/under is 149 points per SportsLine consensus. Before entering any Ohio State vs. Michigan State picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 9 of the 2024-25 season on a 183-130 roll (+2520) on all top-rated college basketball picks dating back to 2023. Anyone following has seen HUGE returns!

The model has simulated Ohio State vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Under and it's also generated a point-spread pick that is hitting well over 70% of the time!

So who wins Michigan State vs. Ohio State? And which side of the spread hits well over 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!