The South Carolina Gamecocks will host the Notre Dame Fighting Irish at 7 p.m. ET on Tuesday as part of the 2023 ACC/SEC Challenge. The Gamecocks are favored by 7.5 points in the latest Mississippi State vs. Georgia Tech odds, and the over/under is 133.

Before entering any Notre Dame vs. South Carolina picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 4 of the 2023-24 season on an 94-61 roll on all top-rated college basketball picks dating back to last season, returning more than $1,800 for $100 players. It is also off to an 8-2 roll on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model has simulated Notre Dame vs. South Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits in over 60% of simulations! 

So who wins Notre Dame vs. South Carolina, and which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!