Notre Dame and St. Mary's play the final game of the opening round in the Maui Jim Maui Invitational on Monday night. Both teams are undefeated heading into their matchup, after the Fighting Irish gutted out an ugly 70-61 win against High Point last Tuesday. St. Mary's started the season with a four-pack of home wins against various mid-major programs to get its 2021-22 campaign started off right. Tip-off from the Michelob Ultra Arena in Las Vegas is at 11:30 p.m. ET.

The Fighting Irish are favored by a single point in the latest Notre Dame vs. Saint Mary's odds from Caesars Sportsbook, and the over-under is set at 131.5. Before you make any Saint Mary's vs. Notre Dame picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Notre Dame vs. Saint Mary's 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Notre Dame vs. Saint Mary's? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!