The ninth-ranked Notre Dame Fighting Irish meet the Florida State Seminoles in a key season-opening non-conference matchup on Sunday. The Fighting Irish went 10-2 a year ago, including an appearance in the College Football Playoffs, while the Seminoles were 3-6 in the 2020 season, shortened by the coronavirus pandemic. 

Kickoff from Doak Campbell Stadium in Tallahassee, Fla., is set for 7:30 p.m. ET. Notre Dame is favored by seven points at Caesars Sportsbook, while the Over-Under is set at 53.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Notre Dame vs. Florida State picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

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Now, it has set its sights on Notre Dame vs. Florida State. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in over 60 percent of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

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