A Big Ten battle will take place on Sunday when the Northwestern Wildcats host the Michigan State Spartans. After making the NCAA tournament the last two seasons, Northwestern is off to a 10-5 start and is 1-3 in Big Ten play while Michigan State is 13-2 and a perfect 4-0 in the conference. However, the Wildcats have won three of the last four head-to-head matchups with the Spartans and they've covered the spread in all four of those meetings.

Tipoff is set for noon ET at Welsh-Ryan Arena in Evanston, Ill. The Spartans are favored by 2.5 points in the latest Northwestern vs. Michigan State odds, while the over/under is 138 points, per SportsLine consensus. Before entering any Michigan State vs. Northwestern picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 10 of the 2024-25 season on a 189-130 betting roll (+2985) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Northwestern vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations!

So who wins Michigan State vs. Northwestern, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!