A Big Ten Conference matchup has the No. 6 Penn State Nittany Lions (4-0) and the Northwestern Wildcats (2-2) playing on Saturday afternoon at Noon ET. For this game, SportsLine consensus odds list the Nittany Lions as a 26.5-point favorite, while the over/under is set at 47 in the latest Penn State vs. Northwestern odds (see up-to-date odds for every game this week on our college football odds page).

Before making any Penn State vs. Northwestern picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model has factored Penn State as one of the best teams in the conference. They are ranked second in the Big Ten in total offense (449.8) and first in yards allowed (219.5). Sophomore quarterback Drew Allar has command and control of the offense. Allar completes 67% of his throws for 903 yards and eight passing touchdowns. He has tossed at least three passing touchdowns in two games this season.

The model also knows Northwestern is coming off their best offensive outing of the season. The Wildcats put up 37 points and 400 total yards in a win over Minnesota. Senior quarterback Ben Bryant was able to move the offense up and down the field consistently, tossing a season-high 396 yards and four passing scores. Senior receiver Bryce Kirtz is an explosive playmaker. In Week 3, Kirtz recorded 10 catches with 215 yards and two touchdowns.

Now, it has set its sights on Penn State vs. Northwestern. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in well over 50% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Penn State vs. Northwestern, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine right now to find out which side of the Penn State vs. Northwestern spread you should be all over Saturday, all from the model that's up almost $2,500 on top-rated CFB spread picks since its inception!