Supremacy in the Big 12 will be on the line when the No. 5 Baylor Bears and No. 9 Iowa State Cyclones collide in a high-stakes women's basketball showdown on Monday at Hilton Coliseum in Ames, Iowa. The winner of the game between the Bears (23-5, 13-3 in Big 12) and Cyclones (24-4, 13-3), who are tied atop the conference standings, will clinch a share of the Big 12 regular season title and take a major step toward winning the title outright with one game remaining. 

Tip-off is scheduled for 7 p.m. ET. The Cyclones are three-point favorites in the latest Iowa State vs. Baylor odds from Caesars Sportsbook, while the Over/Under for total points scored is 144.5. 

Before making any Baylor vs. Iowa State picks, you need to see what women's college basketball experts Calvin Wetzel and Aaron Barzilai have to say.

Barzilai is a Ph.D. from Stanford who served as Director of Basketball Analytics for the Philadelphia 76ers. Five years ago, he founded HerHoopStats.com -- a groundbreaking website that unlocks insights about the women's game. Wetzel, the site's lead betting writer, incorporates his mathematical background and strong knowledge of women's NCAA hoops to turn the site's prediction model into picks. And on Sunday, Barzilai and Wetzel got off to a fast start with SportsLine, correctly picking Iowa (-2.5) to cover against Michigan in a resounding 24-point Hawkeyes victory.

Currently, they are 468-342 overall (+99.97 units, +13.88 percent) in the 2021-22 women's college basketball season.

Barzilai and Wetzel have locked in a confident against-the-spread pick for Iowa State vs. Baylor. We can tell you that they're leaning Under the total, but they know a crucial X-factor that makes one side of the spread a must-back! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Iowa State vs. Baylor on Monday? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Baylor vs. Iowa State spread to jump on, all from the experts who are an outstanding 468-342 on their women's college basketball picks!