The Oklahoma Sooners and Nebraska Cornhuskers renew one of college football's most storied rivalries on Saturday when the two teams collide at Memorial Stadium in Norman, Okla. Kickoff is noon ET. The Sooners are 22.5-point favorites in the latest Oklahoma vs. Nebraska odds from Caesars Sportsbook, while the Over/Under for total points scored is 62.5. (See the latest college football lines for all of this week's games on our college football odds page.)

Before you make any Nebraska vs. Oklahoma picks and college football predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of more than $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Oklahoma has one of the best quarterbacks in the country in Spencer Rattler. A 6-foot-1 sophomore from Phoenix and one of the favorites to win the Heisman Trophy, Rattler has completed 50-of-65 passes for 547 yards and six touchdowns with two interceptions this season. His 76.9 completion percentage ranks second in the country.

On the other side Nebraska has gotten its offense rolling. In the last two weeks, the Huskers have rolled up 633 yards of total offense against Fordham and 516 yards of offense against Buffalo. The offensive output against Fordham was the program's best since churning out 674 yards at Illinois in 2019.

Now the model has simulated Oklahoma vs. Nebraska 10,000 times, and the results are in. We can tell you that the model is leaning Under on the total, and it has generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins the battle between Oklahoma and Nebraska? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to see which side of the Nebraska vs. Oklahoma spread you need to jump on Saturday, all from the computer model that has crushed its college football picks!