There are no pick'ems on the Week 5 NFL schedule, but there are a pair of games with 1-point NFL spreads. Patriots vs. Dolphins has Miami as a 1.5-point favorite, per the Week 5 NFL odds, while Bills vs. Texans has Houston favored by a single point. If you're a fan of playing games with slim NFL lines, then you could combine football predictions from these contests into lucrative Week 5 NFL parlay picks with either money line or NFL ATS picks.

Which NFL trends and NFL tendencies could help with your NFL betting strategy? Before you make any Week 5 NFL picks or NFL parlays, you need to see what SportsLine senior analyst Larry Hartstein has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. Hartstein tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. His weekly Vegas contest selections form the basis of his NFL best bets column, which is 83-55-3 (60.1%, +22.15 units) since its inception in 2022. Anyone who has followed him is WAY UP!

For Week 5, Hartstein has locked in three confident best bets. If you successfully parlay his picks, you're looking at a payout of almost 6-1.

We can tell you Hartstein loves the Broncos (-2.5, 35.5) to cover against the Raiders. "The Broncos return home with momentum after upsetting Tampa Bay and the Jets as huge road dogs. They are giving up 4.2 yards per play, second-fewest in the NFL," Hartstein told SportsLine.

Hartstein also has locked in two other confident Week 5 bets, including backing an underdog who should OVERWHELM an opponent's "shaky defense." You ABSOLUTELY need to see his picks before betting on NFL Week 5.

So what are Hartstein's Week 5 NFL best bets? And which team surprises in Week 5? ... Join SportsLine right now to see Larry Hartstein's Week 5 NFL best bets, all from the expert who is up 22.15 units on NFL ATS picks!