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NFL Week 16 odds, score predictions: SportsLine AI reveals picks for every game on the football schedule

SportsLine AI reveals its NFL picks against the spread, over-under, and money-line for all 16 games in Week 16 of the NFL season

With three weeks remaining in the 2024 NFL season, three of the four divisions in the AFC have already been decided but all four divisions in the NFC are still up for grabs. The Eagles (12-2) can become the first team to secure a home playoff game on Sunday when they visit the Commanders (9-5) for a 1 p.m. ET kickoff. Philadelphia is favored by four on the road in the latest Week 16 NFL odds, up a half-point from the opener, while the over-under is 45.5. The latest Commanders vs. Eagles forecast is calling for sunny skies, light winds out of the north, and temperatures in the 30s. Who should you back in that game and how should you handle all your NFL money line, NFL over-under and NFL spread picks? Before you make any Week 16 NFL picks, be sure to check out the NFL score predictions from the SportsLine AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data then quantitatively evaluating the strength of the opponents defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see a 5-star rating on an Over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has nailed 2,131 4.5- and 5-star prop picks since the start of last season! Anyone who has followed it is WAY UP!

After analyzing every game in Week 16, the AI PickBot says the Cowboys cover comfortably as 4-point home underdogs against the Buccaneers on Sunday Night Football. After starting the season with Super Bowl aspirations, Dallas hit the skids in the middle of the season with a five-game losing streak but the franchise has showed some fight of late. Cooper Rush has led the team to wins in three of four, including wins as outright underdogs against the Commanders and Panthers. The AI PickBot rates a Cowboys cover as an A+ pick and also predicts a 35-29 outright win on average.

SportsLine AI has generated against the spread, over-under, and money-line picks for every game in Week 16! In fact, the AI PickBot has generated 16 HIGHLY-COVETED A+ picks! You ABSOLUTELY NEED to see the AI PickBot's analysis before making any Week 16 NFL bets.

Which NFL bets do you need to make NOW for Week 16? And which must-see NFL picks are worthy of an A+ rating? ... Join SportsLine now to see the top 2024 Week 16 NFL picks, all from the self-learning SportsLine AI PickBot that has nailed a COLOSSAL 2,131 top-rated picks since the start of last season!

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SportsLine Staff
SportsLine Staff

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