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NFL Week 16 betting preview: Broncos-Chargers, Texans-Chiefs and more early picks from Jason La Canfora

NFL insider Jason La Canfora shares his initial picks and lines to watch for Week 16 of the 2024 NFL season.

This is a weird week in the NFL and it's only going to get weirder. I'm making plays on the earlier games and anticipate some movement in the near term on these lines. I'm not sure how much longer some of these totals will be available. There are some significant players dealing with injuries heading into these short-week games as well, and those situations could obviously heavily factor into how the games play out.

There are some totals in some of the less interesting games in Week 16 that have my attention, but I don't expect much early action on them moving the lines. We're focusing on the earlier games and matchups with at least something at stake for one of the teams -- if not both -- in our initial plays.

Before you make your Week 16 picks, you'll want to see what NFL expert Jason La Canfora has to say. La Canfora has broken the games down and found a number of early best bets, including a play on the Thursday night Broncos-Chargers game. You NEED to see his analysis before locking in any NFL picks of your own.

Which lines are worth jumping on right now, and what are the best plays for Broncos-Chargers? Join SportsLine right now to see Jason La Canfora's NFL Week 16 betting primer!

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Jason La Canfora
Jason La CanforaJLC

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