The Saints are on a league-high seven-game losing streak, and they are 3.5-point underdogs, per the latest Week 10 NFL odds, to an Atlanta team that is 4-0 in divisional games this year. Meanwhile, there are just as decisive trends to assist with NFL bets in the Titans vs. Chargers (-7.5) game. Tennessee is a league-worst 1-7 against the spread (ATS) this season, while L.A. is 5-1 ATS as a favorite. Thus, both Atlanta on the money line and the Chargers versus the spread seems like it could be the beginning of a winning Week 10 NFL parlay. 

Which NFL trends and NFL betting lines could help with your NFL betting strategy? Before you make any Week 10 NFL picks or NFL parlays, you need to see what SportsLine senior analyst Larry Hartstein has to say. 

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. Hartstein tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. His weekly Vegas contest selections form the basis of his NFL best bets column, which is 90-63-3 (59%, +20.21 units) since its inception in 2022. Anyone who has followed him is WAY UP!

For Week 10, Hartstein has locked in three confident best bets. If you successfully parlay his picks, you're looking at a payout of almost 6-1.

We can tell you Hartstein loves the Colts (+4.5, 48) to cover at home versus Buffalo. "The Bills are playing their fifth road game in seven weeks. They're coming off an emotional win over their division rival, and they've got the Chiefs on deck. So I can see them getting out of Indy with a win, but not by margin," Hartstein told SportsLine.

Hartstein also has locked in two other confident Week 10 bets, including backing a SHOCKING team whose offense is rolling and averaging "6.5 yards per play overall in its past three games!" You ABSOLUTELY need to see his picks before betting on NFL Week 10.

So what are Hartstein's Week 10 NFL best bets, and which team shocks the NFL? ... Join SportsLine right now to see Larry Hartstein's Week 10 NFL best bets, all from the expert who is up 20.21 units on NFL ATS picks!