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As the 2026 NFL season approaches, bettors will race to sportsbooks to make NFL predictions on the spread, in addition to bets on the money line, total or with player props. One way to get help for all of those is getting score predictions for each game. Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here:
SportsLine expert Eric Cohen has made his exact score predictions for Week 1 of the 2026 NFL season. Before you lock in any NFL picks, make sure you see what Cohen has to say.
A SportsLine expert and host, Cohen is evaluating the entire Week 1 NFL slate and delivers score predictions and logic for each matchup. Since the 2024-25 season, Cohen is 378-191-1 on straight up NFL picks (66%) and was profitable for bettors.
We can tell you that Cohen likes the Texans (+1.5 44.5) to narrowly defeat Buffalo at home. "Houston has won 4 of the last 5 meetings against Josh Allen and Buffalo, each by a single possession. Expect the same in Week 1 between two of the AFC's top contenders. The Texans have the best defense in the NFL and should stifle Allen, while on offense, Houston QB C.J. Stroud needs to make amends for a dreadful finish to last season. Dating back to 2020, each of Houston's three victories over Buffalo has seen them score 22 or 23 points, while Buffalo has scored 19 or 20 in each of those games. History has a funny way of repeating itself. I love the Texans at plus-money this week." Texans 23, Bills 20
In addition, Cohen is calling for a road team to prevail by double-digits, making the alternate lines very appealing! Nailing this result is key to making profitable Week 1 NFL picks. You ABSOLUTELY NEED to see which game it is before locking in any Week 1 NFL score predictions!
Who wins every Week 1 NFL game, and which road team is a must bet? ... Join SportsLine now to get Eric Cohen's Week 1 NFL score predictions and find out today!
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Written by Ross Kelly
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