The latest Week 3 NFL odds have six road teams favored, including the 49ers (-7.5) being the biggest favorite on Sunday against the Rams, who will be without star receivers Cooper Kupp and Puka Nacua. Other away squads giving points include Texans (-2.5) at Vikings, Saints (-2.5) vs. Eagles, and Chiefs (-3.5) at Falcons. Meanwhile, one of the slimmest of the Week 3 NFL spreads has Baltimore as a 1.5-point road favorite over Dallas.

Before you lock in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2024 NFL season on an incredible 187-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 41-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 3 of the 2024 NFL season, and the results are in. 

We can tell you one of the model's strongest Week 3 NFL picks is that the Browns (-6.5, 38.5) cover the spread versus the Giants almost 60% of the time. Another one of its Week 3 NFL predictions: the Bengals (-7.5, 48.5) cover on Monday night versus the Commanders well over 50% of the time. The model also says the Over hits in well over 60% of simulations.

The model has also made the call on who wins and covers in every other NFL game this week and just revealed THREE MUST-SEE UNDERDOGS who win outright, potentially giving you a HUGE payday! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back this week, and which three underdogs should you lock in NOW? ... Join SportsLine NOW to see who wins and covers every single game, all from the model on a 187-130 roll on top-rated NFL picks!