Every matchup on the Week 18 NFL schedule is a divisional game and many are loaded with playoff implications such as Jaguars vs. Titans. Jacksonville will lock up the AFC South with a victory, and the Jags are 3.5-point favorites in the latest Week 18 NFL odds. Other divisional matchups that will shape the NFL playoff picture include Buccaneers vs. Panthers (+4), Falcons vs. Saints (-3), Packers vs. Bears (+3) and Bills vs. Dolphins (+3).

Before you lock in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2023 NFL season on an incredible 181-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 35-21 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 18 of the 2023 NFL season, and the results are in. 

We can tell you one of the model's strongest Week 18 NFL picks is that the Lions (-4) cover the spread versus the Vikings more than 60% of the time. Another of the Week 18 NFL predictions is that the Packers (-3) cover at home against Chicago as they pick up a win that would clinch a playoff spot. The model is also backing the Over (44) in that one. 

The model has also made the call on who wins and covers in every other NFL game this week and just revealed FOUR TEAMS that win outright in nearly 70% of simulations! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back this week, and which four favorites should you lock in RIGHT NOW? ... Join SportsLine NOW to see who wins and covers every single game, all from the model on a 178-129 roll on top-rated NFL picks!