Several divisional battles highlight Sunday's Week 16 NFL schedule, including Eagles vs. Commanders. Philadelphia can clinch the NFC East with a win, and the Eagles won and covered when these teams met earlier this year. Philadelphia is favored by 3.5 points in the Week 16 NFL odds, while another divisional contest in Colts vs. Titans has Indianapolis favored by 3.5 points. If you're looking for larger Week 16 NFL spreads, then you're in luck since there are a pair of touchdown favorites in the divisional matchups, Bengals vs. Browns (+6.5) and Lions vs. Bears (+6.5).

Before you lock in any NFL bets, make sure you see what SportsLine's advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2024 NFL season on an incredible 27-11 hot streak on top-rated NFL picks this year. Longer term, it is on a 207-139 roll on top-rated NFL picks that dates back to the 2017 season and a 61-32 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following has seen HUGE returns!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 16 of the 2024 NFL season, and the results are in.

We can tell you one of the model's strongest Week 16 NFL picks is that the Bengals (-7.5, 47) cover the spread at home against the Browns. The model has Cincy winning by double-digits as it has the Bengals prevailing versus the spread well over 50% of the time. Another one of its Week 16 NFL predictions: the Jets (+3.5, 46.5) cover at home versus the Rams in well over 50% of simulations. The model also says the Under hits 60% of the time.

The model has also made the call on who wins and covers in every other NFL game this week and just revealed FOUR underdogs that outright win! You ABSOLUTELY NEED to see its NFL picks for every game before you make any NFL bets of your own!

So which NFL teams should you back in Week 16, and which four underdogs should you lock in RIGHT NOW? ... Join SportsLine now to see who wins and covers every single NFL game this week, all from the model on a 207-139 roll on top-rated NFL picks!