The opening Sunday of the 2023 NFL season is nearly here, and there's an appetizing slate for September 10. Two historic franchises will clash in Steelers vs. 49ers at 1 p.m. ET, while a rematch of a recent Super Bowl takes place at 4:25 p.m. ET in Eagles vs. Patriots. The Niners are 2.5-point favorites in the latest Week 1 NFL odds, while Philly is a 4.5-point road favorite over New England. Elsewhere, the Ravens are the biggest favorites of the Week 1 NFL schedule as they are giving 10 points versus the Texans.

Before making any NFL picks for Week 1, be sure to see what the SportsLine Projection Model has to say. 

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the 2023 NFL season on an incredible 163-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 17-6 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY up!

Now, the model has evaluated the latest NFL odds, simulated every snap for Week 1 of the 2023 NFL season, and the results are in. 

We can tell you one of the model's strongest Week 1 NFL picks is that the Commanders (-7) cover against the Cardinals in almost 60% of simulations. Another one of its Week 1 NFL predictions: The Vikings (-5) cover the spread at home versus the Buccaneers over 50% of the time.

The model has also made the call on who wins and covers every other NFL game this week and has identified a Super Bowl contender that goes down HARD! You ABSOLUTELY need to see its NFL picks for every single game before locking in your own.

So which NFL teams should you back this week? And which Super Bowl contender goes down? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned over $7,000 in profit on top-rated picks since its inception!