Week 5 of the 2022 NFL schedule features several intriguing matchups, highlighted by the Cowboys visiting the Rams. Los Angeles is a 5.5-point favorite in the latest Week 5 NFL odds at Caesars Sportsbook. Other games with tight NFL spreads include Bengals vs. Ravens (-3.5) on Sunday Night Football, Browns vs. Chargers (-2.5) and Patriots vs. Lions (+3). Before making any NFL picks for Week 5, be sure to see what the SportsLine Projection Model has to say.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2022 NFL season on an incredible 140-105 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, the model has evaluated the latest odds from Caesars, simulated every snap for Week 5 of the 2022 NFL season, and the results are in. 

We can tell you one of the model's strongest Week 5 NFL picks is that the Titans (-2.5) cover against the Commanders in almost 60% of simulations. Another one of its Week 5 NFL predictions: The Jaguars (-7) cover the spread at home against the Texans well over 50% of the time. The model also says the Under (44.5) hits in well over 50% of simulations.

The model has also made the call on who wins and covers every other NFL game this week and says an underdog delivers a HUGE upset! You ABSOLUTELY need to see its NFL picks for every single game before locking in your own.

So which NFL teams should you back this week? And which underdog delivers a HUGE upset? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned almost $7,000 in profit on top-rated picks since its inception!