The Week 6 NFL schedule is loaded with must-see NFL matchups, including Colts vs. Jaguars (-4), Seahawks vs. Bengals (-3), 49ers vs. Browns (+9.5), Eagles vs. Jets (+6.5) and Lions vs. Buccaneers (+3). The Week 6 NFL schedule wraps up on Monday Night Football with a matchup between the Dallas Cowboys and Los Angeles Chargers (+2.5) and also features the Bills (-15) and Dolphins (-14.5) as double-digit favorites. Before making any Week 6 NFL office pool picks, you NEED to see which teams the SportsLine Projection Model is backing in its NFL football pool picks.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2023 NFL season on an incredible 171-119 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 25-11 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

In Week 6, we can tell you the model is high on the Los Angeles Rams (-7) defeating the Arizona Cardinals at home. The model is projecting a 27-20 win for the Rams, who secure the straight-up victory in well over 60% of simulations. Los Angeles' offense is averaging 270.0 passing yards per game this season, which ranks fifth in the NFL. In addition, the Rams are 11-2 in their last 13 meetings with the Cardinals. 

The model has also locked in NFL picks for every Week 6 NFL game and says several favorites struggle BIG-TIME! You ABSOLUTELY need to see which teams the model is backing before locking in your NFL pool picks!

So which teams win outright in Week 6, and which favorites should you avoid? ... Join SportsLine right now to see the SportsLine Projection Model's office pool picks, all from the model that has returned over $7,000 on its top-rated NFL picks!