The NFL Divisional Round features four mouthwatering matchups set to unfold Saturday and Sunday. The Kansas City Chiefs will begin their quest to three-peat when they take on the Houston Texans Saturday at 4:30 p.m. ET, followed by the Detroit Lions hosting the Washington Commanders at 8 p.m. ET. According to the latest NFL Divisional Round betting lines, Kansas City is favored by 8 points, while the Commanders are 9.5-point underdogs. 

The 2025 NFL playoffs continue Sunday when Jalen Hurts and the Philadelphia Eagles host Matthew Stafford and the Los Angeles Rams at 3 p.m. The Eagles have won 13 of their last 14 games and are favored by 6 points. The action wraps up Sunday when the Buffalo Bills face the Baltimore Ravens at Highmark Stadium at 6:30 p.m. ET. Baltimore is favored by 1.5 points, according to the latest NFL Divisional Round odds, while the over/under is 51.5.

SportsLine's advanced NFL model has revealed its exact NFL score predictions for every game of the NFL Divisional Round, which could mean a huge payday of well over 100-1 if any of them hits. Before you lock in any NFL Divisional Round picks, make sure you see what SportsLine's advanced computer model has to say.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the Divisional Round of the 2025 NFL playoffs on a 31-15 hot streak on top-rated NFL picks this year -- a stunning 67% success rate! Longer term, it is on a 211-143 roll on top-rated NFL picks that dates back to the 2017 season and a 65-36 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following could have seen HUGE returns!

Now, the model has evaluated the latest NFL odds, simulated every snap of the NFL Divisional Round, and the results are in.

We can tell you SportsLine's model likes the Philadelphia Eagles (-6, 43.5) to beat the Los Angeles Rams, 28-18. These two teams squared off on Nov. 24 with Philadelphia securing a lopsided 37-20 win on the road. Running back Saquon Barkley had a historic game, recording 26 carries for 255 yards and two touchdowns. Barkley is averaging 145.3 rushing yards per game over his last three contests and he'll likely be heavily involved in Philadelphia's game plan on Sunday. The model expects Barkley to lead the Eagles to victory on Sunday as Philadelphia wins in well over 70% of simulations. 

In addition, the model has locked in its exact score prediction for every other NFL playoff game. Nailing these results is key to making profitable NFL Wild Card Weekend picks. You ABSOLUTELY NEED to see who to pick before locking in any NFL score predictions.

What are the projected scores for every NFL Divisional Round game? And which projected scores could cash for over 100-1? ... Join SportsLine NOW to get NFL Wild Card Weekend score predictions, all from the model on a dominant 65-36 roll!