The Week 16 NFL schedule will conclude with the Green Bay Packers (-14, 42.5) hosting the New Orleans Saints on Monday Night Football. The Saints have been battling injuries all season and life only got worse this week when star running back Alvin Kamara (groin) was declared out. Derek Carr (hand), Chris Olave (concussion) and Taysom Hill (knee) are all out for New Orleans as well, leaving the Saints without their four most prolific playmakers.

However, the potential for Saints role players to step into pivotal roles creates an opportunity to unearth value for NFL daily Fantasy players. So who are the best options in the NFL DFS player pool for Packers vs. Saints and how can you optimize your NFL DFS lineups for this single-game slate? Before making any NFL DFS picks on sites like DraftKings and FanDuel, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him is WAY UP!

Now, McClure has turned his attention to Packers vs. Saints on Monday Night Football and locked in his top daily Fantasy football picks.

We can tell you one of McClure's top NFL DFS picks for Monday Night Football is Saints running back Kendre Miller. He's also targeting Packers quarterback Jordan Love, who has gone four games without an interception after battling turnover issues early in the season. Love is averaging 8.3 yards per pass attempt this season, up from 7.2 yards per pass attempt during his breakout season in 2023.

McClure is also targeting a player who could go off for MASSIVE numbers for Monday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks Saints vs. Packers, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!