The Week 2 NFL schedule starts off with a bang with two top Super Bowl contenders colliding on Thursday Night Football. Patrick Mahomes and the Kansas City Chiefs will host Justin Herbert and the Los Angeles Chargers in a battle between two of the best teams, and arguably the top two quarterbacks, in the NFL. Before locking in any NFL DFS lineups for Thursday Night Football on sites like DraftKings and FanDuel, you NEED to see what Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

In the Broncos vs. Seahawks Week 1 Monday Night Football matchup, Kaylor listed Denver wide receiver Jerry Jeudy as one of his top Showdown DFS picks. The result: Jeudy hauled in 4 passes for 102 yards and a touchdown and was the highest scoring fantasy player in the game.

Now, Kaylor has turned his attention to Chiefs vs. Chargers on Week 2 Thursday Night Football and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for the Chargers-Chiefs TNF matchup is Kansas City All-Pro tight end Travis Kelce. In two games against the Chargers in 2021, Kelce totaled 17 receptions for 295 yards and two touchdowns, and Kaylor sees that trend continuing in Week 2. "Kelce is kind of low-hanging fruit in the NFL DFS world, but he is a must-roster this week and should be considered for Captain/MVP slots. With his track record against the Chargers and his connection with Patrick Mahomes, this should be a no-brainer. I'm projecting a floor of eight targets for Kelce on Thursday night."

Kaylor is also targeting another under the radar option for TNF who could post HUGE numbers and carry your lineups to victory on Thursday night. This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks for Chiefs vs. Chargers on FanDuel and DraftKings? And which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!