The Week 1 NFL schedule wraps up with a primetime matchup between the New York Jets and San Francisco 49ers (-3.5) on Monday Night Football. Kickoff at Levi's Stadium in Santa Clara, California is scheduled for 8:20 p.m. ET. The MNF NFL DFS player pool features several high-end, proven fantasy options, mixed with young, high upside players, meaning there will be plenty of tough decisions to be made when building NFL DFS lineups. Should perennial Pro Bowl candidates like Breece Hall, Aaron Rodgers, Brock Purdy, Brandon Aiyuk, or Garrett Wilson be part of your Monday Night Football DFS lineups or NFL DFS stacks? 49ers running back Christian McCaffrey is inactive with a calf injury.

Before locking in any NFL DFS lineups or NFL DFS stacks for 49ers vs. Jets on Monday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks for SportsLine members throughout the 2022 and 2023 seasons. In 2022, he was all over Travis Kelce's four touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15. In 2023, he hit on Ja'Marr Chase's massive Week 5 performance (15 catches, 192 yards, three TDs), D.J. Moore's eight catches for 230 yards and three touchdowns in Week 14, and De'Von Anchane's breakout performance (233 total yards, four TD's) in Week 3. Anyone who followed his picks is WAY UP!

Now, Kaylor has turned his attention to 49ers vs. Jets on Monday Night Football and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Jets vs.49ers is Jets quarterback Aaron Rodgers. He's also rostering 49ers tight end George Kittle, who could see an increased role with Christian McCaffrey (calf) inactive.

Kaylor is also targeting another under-the-radar player who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

What are the top NFL DFS picks for Jets vs. 49ers on Monday Night Football in Week 1, and which unheralded player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a proven DFS expert who won a Millionaire Maker tournament!