The Nebraska Cornhuskers and Illinois Fighting Illini square off Saturday in the Big Ten opener at Memorial Stadium in Champaign, Ill. Kickoff is set for 1 p.m ET. The Cornhuskers are favored by seven points in the latest Illinois vs. Nebraska odds from Caesars Sportsbook, and the Over-Under is set at 52.5. 

Before you make any Nebraska vs. Illinois picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. For the 2020 season, it went 56-37 on all top-rated picks and returned over $1,200 on its top-rated spread and over-under picks. Anyone who has followed it has seen huge returns.

The Cornhuskers went 3-5 and finished fifth in the West Division last season and want to come out strong with coach Scott Frost entering the season on the hot seat. Nebraska is 8-7 against the spread on the road and 13-13 ATS in conference games since Frost was hired in 2018.   

Illinois was seventh in the West in 2020 at 2-6, and new coach Bret Bielema's team beat Nebraska 41-23 in Lincoln last season. The Huskers turned the ball over five times in the loss. The Fighting Illini are 9-7 ATS as an underdog the past two seasons, including 4-2 at home.    

Now, the model has simulated Illinois vs. Nebraska 10,000 times, and the results are in. We can tell you that the model is projecting 54 total points, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Illinois vs. Nebraska? And which side of the spread is hitting in 60 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.