The Colorado Buffaloes will aim for their fourth straight win over the Nebraska Cornhuskers when they meet on Saturday night. Colorado has never won four in a row in the series that began in 1898, with Nebraska holding a 49-21-2 lead all-time. The Buffaloes opened the season with a 31-26 win over North Dakota State, while the Cornhuskers rolled to a 40-7 win over UTEP. 

Kickoff is set for 7:30 p.m. ET on Saturday at Tom Osborne Field at Memorial Stadium. Nebraska is favored by 6.5 points in the latest Nebraska vs. Colorado odds, while the over/under is 55.5 points, per SportsLine consensus. Before entering any Colorado vs. Nebraska picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model has simulated Nebraska vs. Colorado 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in more than 60% of simulations!

So who wins Colorado vs. Nebraska, and which side of the spread hits more than 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!