The Minnesota Vikings will host the San Francisco 49ers on Monday Night Football at U.S. Bank Stadium. Kickoff is set for 8:15 p.m. ET. The latest 49ers vs. Vikings odds list San Francisco as seven-point favorites and the over/under for total points scored is 43. Before you make any Vikings vs. 49ers picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2023 NFL season on an incredible 172-120 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 26-12 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

The model knows San Francisco star running back Christian McCaffrey (NFL-high 553 rushing yards) is questionable, but is expected to play. Receiver Brandon Aiyuk (454 receiving yards) and tight end George Kittle (18 receptions) can fill any voids. San Francisco leads the NFL in scoring defense (14.5 points per game) and is second on offense (30.7).

The model also is aware that Vikings quarterback Kirk Cousins is second in the NFL with 1,679 passing yards, with 14 TD passes and four interceptions. Star receiver Justin Jefferson is out, but tight end T.J. Hockenson (36 receptions) has become a focal point. Jordan Addison and K.J. Osborn have combined for 491 receiving yards and six touchdowns.

Now, the model has analyzed 49ers vs. Vikings on Monday Night Football. We can tell you the model is leaning Under the total, and it also says one side of the spread has ALL the value! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins 49ers vs. Vikings on Monday Night Football? And which side of the spread has ALL the value? ... Join SportsLine right now to find out which side of the Vikings vs. 49ers spread is a MUST-BACK, all from the model on a 26-12 roll on NFL picks!