It's another loaded Friday MLB schedule, with 15 games on tap as teams try to make their moves in hopes of grabbing postseason spots. The battle in the AL East rages, and the Baltimore Orioles and Tampa Bay Rays both are in the midst of tough series. Baltimore (62-40) sits atop the AL East, 1.5 games ahead of Tampa Bay (62-43). The Orioles are hosting the Yankees, and Tampa Bay is in Houston to continue their series with the Astros.    

The Yankees are -130 favorites (risk $130 to win $100), while the Orioles are priced at +110 in the latest Caesars Sportsbook MLB odds. The over/under for total runs scored is 8.5. The Rays and Astros are even on the money line (risk $110 to win $100), with the over/under set at 8.5. (See up-to-date lines for every game on our MLB odds page.)

The 15-game Friday MLB schedule offers plenty of opportunities for wagers, and combining your favorite picks into a parlay can pay off big. Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It entered Week 18 of the 2023 MLB season 48-36 (+192) on all top-rated MLB picks this season and has excelled on top-rated run-line picks, going 11-2 (+604). Anybody following has seen big returns!

Now, the model has set its sights on the MLB schedule for Friday and has generated a four-leg parlay that would pay almost 8-1. The parlay doesn't start until 7:05 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the Yankees (-130) to defeat the Orioles (7:05 p.m. ET), but the model has locked in three other selections for the parlay, including TWO run-line underdogs! You ABSOLUTELY need to see the predictions before locking in any MLB picks of your own.

So which play is a MUST-BACK on Friday night's MLB schedule? And which teams do you need to include in your parlay for a payout of nearly 8-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is on an 11-2 run on top-rated run-line picks!