The No. 6 Missouri Tigers will face off against the No. 24 Boston College Eagles on Saturday afternoon in one of two ranked vs. ranked matchups on the Week 3 college football schedule. Missouri has opened the season with a pair of shutout wins, outscoring Murray State and Buffalo by a combined tally of 89-0. Boston College knocked off then-No. 10 Florida State in its season opener before cruising to a 56-0 win over Duquesne last week. 

Kickoff is set for 12:45 p.m. ET on Saturday at Memorial Stadium/Faurot Field. Missouri is favored by 16.5 points in the latest Missouri vs. Boston College odds, while the over/under is 54 points, per SportsLine consensus. Before entering any Boston College vs. Missouri picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks and is off to a 4-0 start on over/under picks this season. Anyone who has followed it has seen strong returns.

The model has simulated Missouri vs. Boston College 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 70% of simulations. You can only see the pick at SportsLine.

So who wins Missouri vs. Boston College? And which side of the spread hits well over 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.