The No. 5 seed Michigan Wolverines (25-9) look to build on their Big Ten Tournament win as they take on the No. 12 seed UC San Diego Tritons (30-4), the Big West Champions, in the first round of the 2025 NCAA Tournament on Thursday.

Tip-off from Ball Arena in Denver is set for 10 p.m. ET. The Wolverines are 2.5-point favorites in the latest Michigan vs. UC San Diego odds via SportsLine consensus, while the over/under for total points is 142.5.

Before making any UC San Diego vs. Michigan picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated UC San Diego vs. Michigan 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread cashes in well over 50% of simulations!

So who wins UC San Diego vs. Michigan, and which side of the spread cashes in well over 50% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!