The No. 12 Michigan Wolverines will host the No. 14 Michigan State Spartans in an exciting rivalry showdown Friday night. Michigan currently holds a one-game lead over Michigan State atop the Big Ten standings, and the Wolverines are riding a six-game winning streak. Michigan State is coming off back-to-back wins, including a 75-66 win over No. 13 Purdue Tuesday.   

Tipoff is set for 8 p.m. ET on Friday at the Crisler Center. Michigan is favored by 3.5 points in the latest Michigan vs. Michigan State odds, while the over/under is 150 points, per SportsLine consensus. 

Before entering any Michigan State vs. Michigan picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 16 of the 2024-25 season on a 213-158 betting roll (+1675) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Michigan vs. Michigan State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Michigan State vs. Michigan, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!