The No. 1 seed Auburn Tigers will play in just their second Sweet 16 in 11 years under head coach Bruce Pearl when they take on the No. 5 seed Michigan Wolverines on Friday. Auburn, the No. 1 overall seed in the 2025 NCAA Tournament, had a 20-point victory over Alabama State in the first round, followed by an 82-70 win over No. 9 seed Creighton in the second round. Michigan defeated No. 12 seed UC San Diego 68-65 in the first round before knocking off No. 4 seed Texas A&M 91-79 in the second round to advance to its first Sweet 16 since 2022.

Tipoff from the State Farm Arena in Atlanta, Ga., is set for 9:39 p.m. ET. Auburn is an 8.5-point favorite in the latest Michigan vs. Auburn odds from SportsLine consensus, while the over/under for total points scored is 154.5. Auburn is the -433 favorite on the money line.

Before making any Michigan vs. Auburn picks, you won't want to miss the college basketball predictions from red-hot college basketball expert Larry Hartstein.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. He also has been a profitable college basketball expert. Hartstein is 17-6 (+1040) on his last 23 picks in Michigan games. In his last 104 against-the-spread college basketball picks, he has gone 61-43-1, returning a profit of nearly $1,300 to his followers! You MUST see his 2025 NCAA Tournament picks below before making any of your own.

For Michigan vs. Auburn, Hartstein is leaning Over on the total and he also found a critical X-factor that has him jumping on one side of the spread. You ABSOLUTELY NEED to see these picks before locking in any 2025 NCAA Tournament picks of your own.

So who wins Michigan vs. Auburn and which side of the spread should you be all over? Join SportsLine right now to see which side of the spread you need to jump on, all from a red-hot college basketball expert who is on a 17-6 (+1040) run over his last 23 Michigan picks!