The Massachusetts Minutemen take on the Penn State Nittany Lions at 7 p.m. ET on Monday at the William D. Mullins Center. After opening the season with a win against UMBC, UMass suffered a setback in a lopsided loss to Yale last Friday. Penn State came away with a win in its season-opener against Youngstown State on November 10, 75-59. You can watch Monday night's matchup live on CBS Sports Network.

The Nittany Lions are favored by four points in the latest UMass vs. Penn State odds from Caesars Sportsbook, and the over-under is set at 142.5. Before you make any Penn State vs. Massachusetts picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Massachusetts vs. Penn State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Massachusetts vs. Penn State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks ... If you're already a member, see the picks below!