No. 7 Ohio State hasn't lost since falling short against No. 8 Oregon earlier this season and will host Maryland on Saturday. The Terrapins suffered their first loss of the season against No. 3 Iowa last Friday but hope to avoid a second straight blowout. Kickoff is set for 12 p.m. ET at Ohio Stadium. The Buckeyes are 21.5-point favorites in the latest Maryland vs. Ohio State odds from Caesars Sportsbook, while the Over/Under for total points scored is 71.5. (See the latest college football lines for all of this week's games on our college football odds page.)

Before making any Maryland vs. Ohio State picks and college football predictions, see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It also enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

The model knows that Maryland's passing attack is dangerous. Taulia Tagovailoa ranks 10th in passing yards with 1,497. His top target is Dontay Demus Jr., who has hauled in 28 passes for 507 yards and three touchdowns this season. The duo will look to test the home team's secondary

The model also knows that Ohio State has a strong ground game. TreVeyon Henderson has rushed for 510 yards and seven scores,mwhile averaging a staggering 9.4 yards per carry. He's one of three Buckeyes players who've eclipsed 200 rushing yards in 2021. Only Auburn and Florida average more yards per rush than Ohio State.

Now the model has simulated Maryland vs. Ohio State 10,000 times, and the results are in. We can tell you that the model is leaning Under the total, and it says one side of the spread that's hit in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

Who wins Maryland vs. Ohio State matchup? And which side of the spread hits in almost 60 percent of simulations? ... Join SportsLine right now to see which side of the Maryland vs. Ohio State spread you need to jump on Saturday, all from the computer model that has crushed its college football picks!