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Marquette vs. Villanova odds, score prediction, time: Feb. 21, 2025 picks by proven college basketball model

SportsLine's model has locked in its college basketball best bets for the No. 16 Marquette Golden Eagles vs. Villanova Wildcats on Friday

By@SportsLinePublished: Feb 21, 2025 9:50PM UTC . 2 min read

Big East teams on contrasting streaks will square off as part of Friday's college basketball schedule as No. 16 Marquette visits Villanova. The Golden Eagles (20-6, 11-4) have won back-to-back games after losing their previous three contests. Meanwhile, the Wildcats (15-12, 8-8) have dropped two in a row after winning their prior three matchups. Marquette prevailed 87-74 when these rivals last met on Jan. 24.

Tipoff is at 7 p.m. ET from the Finneran Pavilion in Villanova, Pa. The Golden Eagles are 1.5-point favorites in the latest Villanova vs. Marquette odds from SportsLine consensus, while the over/under for total points scored is 142.5. 

Before making any Marquette vs. Villanova picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 16 of the 2024-25 season on a 213-158 roll (+1675) on all top-rated college basketball picks dating back to 2023. Anyone following could have seen HUGE returns!

The model has simulated Villanova vs. Marquette 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits in more than 60% of simulations!

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