No. 10 Marquette will try to keep pace with St. John's atop the Big East standings when it hosts Villanova on Friday night. The Golden Eagles suffered their first conference loss against Xavier last Saturday before beating Seton Hall on the road earlier this week. Villanova has lost three of its last four games, falling to Georgetown in a 64-63 thriller on Monday.  

Tipoff is set for 7 p.m. ET on Friday at Fiserv Forum. Marquette is favored by 9.5 points in the latest Marquette vs. Villanova odds, while the over/under is 143 points, per SportsLine consensus. Before entering any Villanova vs. Marquette picks, you'll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 12 of the 2024-25 season on a 199-138 betting roll (+2692) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Marquette vs. Villanova 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 60% of simulations. You can only see the pick at SportsLine.

So who wins Marquette vs. Villanova? And which side of the spread hits over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.