The No. 6 St. John's Red Storm will try to close the regular season on a six-game winning streak when they face the No. 20 Marquette Golden Eagles on Saturday afternoon. St. John's has already secured the Big East regular-season title, and it is coming off a 71-61 win over Seton Hall last weekend. Marquette is tied with UConn for third place in the league standings following a 72-66 loss to the Huskies on Wednesday.    

Tipoff is set for noon ET on Saturday at the Fiserv Forum. Marquette is favored by 3.5 points in the latest Marquette vs. St. John's odds, while the over/under is 144 points, per SportsLine consensus. 

Before entering any St. John's vs. Marquette picks, you'll want to see the college basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 18 of the 2024-25 season on a 221-162 betting roll (+1895) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen HUGE returns.

The model has simulated St. John's vs. Marquette 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations!

So who wins St. John's vs. Marquette? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks!