The No. 21 Missouri Tigers host the No. 23 LSU Tigers in an SEC showdown at noon ET on Saturday. For this game, SportsLine consensus lists LSU as a 5.5-point favorite, while the over/under is set at 64.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any LSU vs. Missouri picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of more than $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows LSU's offense is flying high. LSU is averaging 44.0 points per game, No. 7 in FBS this season, and the team is also averaging more than 550 total yards per game. LSU ranks in the top six nationally in passing yards (353.4 per game), yards per play (7.8), and third down efficiency (57.6%). The model also knows Missouri brings strong defensive characteristics. Missouri is giving up fewer than 21 points per game and 5.0 yards per play this season. Missouri also leads the SEC in rushing yards allowed (74.8 per game) and yards per carry allowed (2.5) to begin the 2023 campaign.

Now, it has set its sights on LSU vs. Missouri. We can tell you the model is leaning Under the total, and it also says one side of the spread hits in more than 50% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins LSU vs. Missouri? And which side of the spread hits in more than 50% of simulations? ... Join SportsLine right now to find out which side of the LSU vs. Missouri spread you should be all over Saturday, all from the model that's up more than $2k on top-rated CFB picks since its inception!