We've got another exciting Western Conference matchup on Monday's NBA schedule as the Los Angeles Lakers will host the San Antonio Spurs. Los Angeles is 20-16 overall and 12-5 at home, while San Antonio is 18-19 overall and 6-11 on the road. The Lakers have won each of their first two meetings this season, both coming in San Antonio, with the Lakers most recently defeating the Spurs 119-101 on Nov. 27. The Lakers are playing their first game since having their last two contests postponed due to the devastating wildfires in the Los Angeles region. 

Tipoff is set for 10:30 p.m. ET from Crypto.com Arena in Los Angeles, Calif. The Lakers are favored by 3.5 points in the latest Spurs vs. Lakers odds, according to the SportsLine consensus. The over/under is 220.5 points. Before entering any Lakers vs. Spurs picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 13 of the 2024-25 NBA season on a sizzling 135-97 roll on all top-rated NBA picks dating back to last season, returning well over $3,000. Anyone following could have seen HUGE returns!

The model has simulated Spurs vs. Lakers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that hits almost 60% of the time. You can only see the pick at SportsLine.

So who wins Spurs vs. Lakers? And which side of the spread hits almost 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks!