The Los Angeles Lakers take on the San Antonio Spurs in a Western Conference clash on Wednesday. Tipoff is set for 8 p.m. ET. For this game, SportsLine consensus lists the Lakers as 3-point favorites, while the over/under is 231.5 (see up-to-date odds for every game this week on our NBA odds page). LeBron James (calf) and Anthony Davis (adductor/hip) are listed as questionable.

Before making any Lakers vs. Spurs picks, you NEED to check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 8 of the 2023-24 NBA season on a sizzling 97-51 roll on all top-rated NBA picks dating back to last season, returning more than $4,000. Anyone following it has seen HUGE returns!

The model knows the Lakers have a strong baseline on defense. Los Angeles is allowing fewer than 1.11 points per possession this season while leading the league in free throw prevention. The Lakers are also in the top 10 of the NBA in opponent field goal percentage and defensive rebound rate. Los Angeles is also facing a San Antonio team that is last in the league in offense, scoring fewer than 1.06 points per possession.

The model also knows the Spurs have a gem in Victor Wembanyama. The No. 1 overall pick in the 2023 NBA Draft is off to a hot start in his rookie season, averaging 18.8 points per game. Wembanyama is also in the top 10 of the league with 10.6 rebounds per game and in the top three with 2.8 blocked shots per game. In the last seven games, Wembanyama is averaging 19.3 points, 13.6 rebounds and 3.3 blocks per game.

Now, it has set its sights on Lakers vs. Spurs. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in 60% of simulations! You ABSOLUTELY need to see it before locking in any NBA picks.

Who wins Lakers vs. Spurs? And which side of the spread hits in 60% of simulations? ... Join SportsLine right now to find out which side of the Lakers vs. Spurs spread you should be all over Wednesday, all from the model on a 97-51 roll on top-rated NBA picks!